Kristalose - When the going gets tough...

What Is Constipation?

One of most common gastrointestinal complaints in the United States is constipation. Around 16% of adult Americans have constipation.3

Constipation is the uncomfortable passing of small, hard, dry amounts of stool, usually fewer than 3 times a week. When constipation arises, bowel movements become difficult and painful.3

Signs of constipation include infrequent bowel movements, difficulty and discomfort with bowel movements, low stool volume, a sense of incomplete evacuation or stools that are harder than usual.

Unfortunately, constipation is something most people experience from time to time. Occasional constipation is generally not as clinically significant as being constipated all the time, which is classified as chronic.

Understanding the causes of constipation and learning how to prevent them can assist patients in finding a treatment that will bring them relief.

KRISTALOSE® (lactulose) For Oral Solution is indicated for the treatment of constipation. In patients with a history of chronic constipation, lactulose therapy increases the number of bowel movements per day and the number of days on which bowel movements occur.

KRISTALOSE® is contraindicated in patients who require a low-galactose diet and should be used with caution in diabetics. Initial dosing may produce flatulence and intestinal cramps, which are usually transient. Excessive dosage can lead to diarrhea with potential complications, such as loss of fluids, hypokalemia, and hypernatremia. Nausea and vomiting have been reported.

Safety and effectiveness in pediatric patients have not been established.

3. Constipation. National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved August 1, 2019.