About Kristalose

Patients Prefer Kristalose1
  • Once-daily powder dosing
  • Virtually tasteless
  • Palatable – not thick or sticky
  • No need to take with food
Portable & Convenient
  • Portable, pre-measured powder packets
  • No bulky or heavy bottles to carry
Powder Form of Lactulose
  • Dissolves quickly in just 4oz of water
  • The only powder available by prescription
  • Lactulose has been FDA-approved for over 40 years
Proven Safe & Effective
  • No negative pregnancy test or concomitant use of contraception required
  • Less than 1.5 calories per 10g dose
  • Usually works within 24 – 48 hours


KRISTALOSE® (lactulose) For Oral Solution is indicated for the treatment of constipation. In patients with a history of chronic constipation, lactulose therapy increases the number of bowel movements per day and the number of days on which bowel movements occur.

KRISTALOSE® is contraindicated in patients who require a low-galactose diet and should be used with caution in diabetics. Initial dosing may produce flatulence and intestinal cramps, which are usually transient. Excessive dosage can lead to diarrhea with potential complications, such as loss of fluids, hypokalemia, and hypernatremia. Nausea and vomiting have been reported.

Safety and effectiveness in pediatric patients have not been established.

1. Barish CF, Kaelin B. Comparison of preference and safety of powder and liquid lactulose in adult patients with chronic constipation. Clin Exper Gastroenterol 2010; 3: 153-158.